Validations

Neuron

We validated neuron models with experimental data on post-synaptic potential (PSP) (Magee and Cook, 2000) and back-propagating action potential (bAP) attenuation (Golding et al., 2001).

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bAP
PSP
bAP

Action potentials generated at the soma or axon initial segment (AIS) travels backwards into the dendrites. The height of the AP is generally smaller at the level of the dendrites than at the level of the soma. The amount of decrement depends on the distance from the soma.

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PSP

Post-synaptic potential (PSP) measured at the soma is generally smaller than the PSP measured at the level of the synapse. The amount of decrement depends on the distance from the soma.

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